August 18th, 2024 Recent Publications Harnessing the Power of Translatomics Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, we bring a focus to the research of tRNA modifications. Starting off, Tresky et al. uncover the role of TRMT10A in translation […]
Translatomics for tRNA modifications Read More »
August 11th, 2024 Recent Publications Harnessing the Power of Translatomics Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Lin et al. unveils that histone deacetylase Hos2 regulates protein expression noise by modulating the translation machinery in yeast. Rodriguez et al. discovered
Translatomics for Hos2, 5’UTR and ribosomal stalling Read More »
August 4th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Leow et al. underlined that the regulation of Water-Soluble Palm Fruit Extract improved insulin sensitivity, and therefore, attenuated the progression of diabetes and
Translatomics for diabetes, RNA m5C and TuMV Read More »
Translatomics in Action: Respiratory Illnesses Respiratory illnesses encompass a wide range of disorders affecting the lungs and other parts of the respiratory system. These illnesses can vary from acute conditions like the common cold to chronic diseases such as asthma, lung cancer and as seen in recent times, SARS-CoV-2. The impact of respiratory illnesses on
Translatomics for Respiratory Illnesses Read More »
July 28th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Ma et al. suggested that targeting N-acetyltransferase 10 could promote heart repair. Shichino et al. stated that eIF4A1 selectively binds to TOP mRNAs
Translatomics for heart regeneration, eIF4A and sfRNA Read More »
July 21st, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Burgers et al. examines effects of HT and HHT effects on inflammation in a mouse peritonitis model and human endothelial cells, focusing on endothelial activation
Translatomics for inflammations, anti-RBP and ascorbate Read More »
July 14th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Kim et al. induced stress on the eIF4F complex to investigate its function in modulating gene expression to promote cellular survival. Musaev et
Translatomics for 3B7N, eIF4F complex and UPF1 Read More »
July 7th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Ero et al. showed that the formation of large ribosomal subunit (50S) of E. coli was essential for its ribosome biogenesis, contributing to
Translatomics for rRNA, eIF4G2 and mRNA decay Read More »
By Gary Loughran, Head of Biology Introduction Mutations that introduce a premature termination codon (PTC) into the mRNA lead to the synthesis of truncated and usually non-functional proteins that may cause disease. Furthermore, mRNA surveillance pathways, such as the nonsense-mediated mRNA decay (NMD) pathway, can compound the impact of PTCs by degrading mutant mRNAs to
June 30th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Awad S et al. find that longer genes in S. cerevisiae have lower ribosome drop-off rates, while Rocha AL et al. characterise the
Translatomics for translational efficiency, uORFs and tRNA Read More »
