Author name: Oscar Ting

Revolutionizing Gene Annotation: The Power of Ribosome Profiling

By Gary Loughran, Head of Biology Gene annotation is a cornerstone of genomics, providing insights into the functional elements of the genome and enabling researchers to understand the roles of genes in health, disease, and development. However, due to the complexity of many genomes, gene annotation is a daunting task, and traditional methods often fall […]

Revolutionizing Gene Annotation: The Power of Ribosome Profiling Read More »

Translatomics for iron depletion and sex chromosomes

June 23rd, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Barlit et al. present a comprehensive genome-wide analysis of protein synthesis in yeast under iron scarcity using ribosome profiling (Ribo-Seq). Wei et al.

Translatomics for iron depletion and sex chromosomes Read More »

Translatomics for ribosome composition changes and uORFs

June 16th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, David, F. et al investigated ribosome composition changes in human cardiomyocytes under ER stress induced by tunicamycin and Shepelev N.M. et al investigated

Translatomics for ribosome composition changes and uORFs Read More »

Translatomics in Melanoma: Unveiling Therapeutic Challenges

Melanoma Melanoma is a particularly aggressive cancer, well known for its ability to rapidly metastasize to other organs, making early diagnosis crucial. Alarmingly, it is also currently one of the fast growing cancers in the Western world (1), and so further research in this area is particularly important. Control of protein synthesis in cancer is

Translatomics in Melanoma: Unveiling Therapeutic Challenges Read More »

Translatomics for stress response, EBV, m6A and autism

June 9th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Hofmann et al. investigate the role of ATF6 during the complexities of cardiac hypertrophy, while Zhang et al. uncover a novel translational mechanism

Translatomics for stress response, EBV, m6A and autism Read More »

Translatomics for translation efficiency, tRNA and FlhDC

June 2nd, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Pilling et al. investigate differences in mRNA and protein profiles between male and female neutrophils, revealing variations that could explain disparities in disease

Translatomics for translation efficiency, tRNA and FlhDC Read More »

Translatomics for immunity, proteome and Epstein-Barr virus

May 26th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Litsios et al. observe cell cycle-specific dynamics in transcription, translation, and the proteome, Seedhom et al. elucidate translation dynamics during activation of lymphocytes,

Translatomics for immunity, proteome and Epstein-Barr virus Read More »

Translatomics for 5mC, Coronavirus and METTL16

May 19th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Dai et al. present a newly developed technique they call ultrafast bisulfite sequencing that can rapidly and accurately detect 5-methylcytosine modification in both

Translatomics for 5mC, Coronavirus and METTL16 Read More »

Translatomics for piRNA, breast cancer and mitochondria

May 12th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Vrettos et al. revealed the crucial role of N-terminal arginine methylation in MIWI proteins for regulating piRNA amplification and maintaining gene stability during

Translatomics for piRNA, breast cancer and mitochondria Read More »

Translatomics for translation kinetics, GCN2 and phages

May 5th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Popper et al. examined global translation kinetics across various cell types using timed ribosome runoff, proteomics, and electron microscopy. Misra et al. investigated

Translatomics for translation kinetics, GCN2 and phages Read More »

Scroll to Top