Author name: Oscar Ting

Translatomics for circRNA, polysome linked miRNA and lipids

March 24th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Huang et al. show how ribo-seq helped identify cryptic immunopeptides expressed from a circular RNA. Wang et al. used that polysome profiling to […]

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Translatomics for HERV, ribosome collisions and SARS-CoV-2

March 17th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Dopkins et al. (2024) perform the first large-scale analysis of HERV translation in healthy tissues using publicly available ribosomal profiling datasets. Fedry et

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Translatomics for rRNA modifications, frameshifting and ISR

March 10th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Xu et al. uncover a novel functionality of rRNA modifications in selective mRNA translation in colorectal cancer, while Ren et al. hypothesise a

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Translatomics for lncRNA, chromosomes and neurodevelopment

March 3rd, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, we delve into an intriguing study by Li et al. that explores the responsiveness of small peptides, encoded by lncRNA, to space conditions

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Translatomics for lncRNA, AltORFs and bacterial translation

February 25th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Li et al. characterise long non-coding RNAs derived from miRNA loci, Leblanc et al. present OpenProt 2.0, a new proteomics platform for functional

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Translatomics: A New Era in Cancer Research

The rapidly evolving field of cancer research has seen significant advances in understanding the complex mechanisms underpinning tumour development, progression, and resistance to therapy. Recent studies leveraging translatomics have provided profound insights into the role of mRNA translation and its regulation in cancer, offering new avenues for therapeutic intervention and diagnostic approaches. This blog post

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Translatomics for 5′ TOP RNA, neoantigens and eIF4E1

February 18th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Mansouri-Noori et al. investigate the role of Slr1p in regulating mRNA translation and decay in S. pombe. Gurung et al. look at development

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Translatomics for ncORFs, cancer treatment and rare codons

February 11th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Zheng et al. used Ribo-seq to reveal how cancer relies on cryptic non-canonical open reading frames for growth. Jia et al. focus on

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Translatomics for ribosome stalling, SARS-CoV-2 and cancer

February 4th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Fedorovskiy et al. explored how diverse small-molecule translation inhibitors impact SG formation during severe oxidative stress induced by sodium arsenite. Kim et

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Translatomics for eIF2α, cancer and non-canonical ORFs

January 28th, 2024 Recent Publications Harnessing the Power of Translatomics. Every week we provide a digest of a small number of recent interesting papers in the field of translatomics. In this week’s Sunday papers, Amiri et al. (2024) aim to uncover how phosphorylated (p)-eIF2α influences translational control of naive pluripotency. Hofman et al. (2023) conducted ribosome

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