At EIRNA Bio, we have developed our sORF Explorer platform dedicated to uncovering the vast, uncharted world of small peptides with significant biological functions. These previously overlooked short proteins, often translated from non-coding RNAs or small open reading frames (sORFs), are emerging as key regulators in cellular processes, disease mechanisms, and therapeutic innovation.

Why Focus on Micropeptides?

For decades, research has focused on large, well-characterized proteins. However, advancements in ribosome profiling and translatomics have revealed that many functional peptides remain hidden within the genome, influencing pathways in cancer, neurodegeneration, and immune regulation. sORF Explorer enables systematic identification and characterization of these molecules, unlocking new opportunities for drug development and biomarker discovery.

Key Features:

• Innovative Identification Techniques: Leveraging advanced ribosome profiling to pinpoint actively translated micropeptides.
• Therapeutic Potential: Can be used as the basis to explore novel druggable targets and micropeptide-based therapeutics.
• Cross-Disciplinary Applications: Spanning oncology, rare diseases, regenerative medicine, and immunotherapy.

By harnessing the power of sORF Explorer, researchers can expand the drug discovery landscape, uncover novel mechanisms of disease, and open new frontiers in precision medicine.